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12 Jun Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. It also facilitates and regulates the entry of many substances that are critical to These extra-barrier functions allow the BBB to influence the homeostatic, .

' Bypassing' the BBB can also be an effective strategy, especially for.

Description:In its neuroprotective role, the blood—brain barrier functions to hinder the delivery of many potentially important diagnostic and therapeutic agents to the brain. Therapeutic molecules and antibodies that might otherwise be effective in diagnosis and therapy do not cross the BBB in adequate amounts. Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB.

Views: 8118 Date: 2018-04-19 Favorited: 42 favorites

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